Karunesh Remedies


Glimepiride Usp-ep-bp-ip

Synonyms of Glimepiride : 3-ethyl-4-methyl-N-(4-[N-((1r,4r)-4-methylcyclohexylcarbamoyl)sulfamoyl]phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide

Formula of Glimepiride : C24H34N4O5S

CAS of Glimepiride : 93479-97-1

Uses of Glimepiride : Anti Diabetic, Inhibition of ATP-dependent potassium channels (sulfonylurea); treatment of diabetes mellitus

Specifications (As per USP/BP/EP/IP)

Description A white or almost white crystalline powder.
Solubility Practically insoluble in water, soluble in dimethylformamide, slightly soluble in methylene chloride, very slightly soluble in methanol.
Identifications by IR IR Spectrum matches with that of standard
Relative Impurities
Impurity B
Impurity D
Impurity C
Unspecified Impurities
Sum of Impurities other than B

Not More than 0.4%
Not More than 0.2%
Not More than 0.1%
Not More than 0.1%
Not More than 0.5%
Impurity A Not More than 0.8%
Water (By K.F) Not more than 0.5% w/w
Heavy Metals Not more than 10 ppm
Sulphated Ash Not more than 0.1% w/w.
Assay By HPLC 97% to 102% (anhydrous basis)
Particle Size 100% less than 10 micron